轉(zhuǎn)基因大豆與不育、嬰兒死亡率有關(guān)聯(lián)
GM soy linked to sterility, infant mortality
Wednesday, 21 April 2010 20:09
轉(zhuǎn)基因大豆與不育,嬰兒死亡率有關(guān)聯(lián)
星期三,2010年4月21日20:09
faraway2010譯 http://14099853.blog.hexun.com/49023617_d.html
http://www.gmwatch.org/latest-listing/1-news-items/12160-gm-soy-linked-to-sterility-infant-mortality
摘錄:“我們沒(méi)有權(quán)利使用轉(zhuǎn)基因生物,直到我們了解可能產(chǎn)生的不利影響,不僅對(duì)自己,而且對(duì)后代。我們一定要全面詳細(xì)地研究以澄清這一點(diǎn)?!? 俄羅斯生物學(xué)家Alexey V. Surov
Genetically Modified Soy Linked to Sterility, Infant Mortality
Jeffrey Smith
Huffington Post, April 20 2010
http://www.huffingtonpost.com/jeffrey-smith/genetically-modified-soy_b_544575.html
“這項(xiàng)研究只是例行公事,”俄羅斯生物學(xué)家Alexey V. Surov說(shuō),在本世紀(jì)會(huì)以掩飾的方式結(jié)束。Surov和他的同事發(fā)現(xiàn),如果孟山都公司的轉(zhuǎn)基因(GM)大豆,在美國(guó)大豆田里,91%種植轉(zhuǎn)基因大豆,導(dǎo)致生長(zhǎng)或繁殖問(wèn)題。他的發(fā)現(xiàn)可能鏟除一個(gè)數(shù)十億美元的產(chǎn)業(yè)。
在喂食倉(cāng)鼠兩年經(jīng)歷了三代后,那些食用轉(zhuǎn)基因食物的,尤其是那組食用最大量的的轉(zhuǎn)基因大豆的倉(cāng)鼠,顯示出災(zāi)難性的結(jié)果。在產(chǎn)生第三代之前,大多數(shù)喂食轉(zhuǎn)基因大豆的倉(cāng)鼠失去生育能力,它們生長(zhǎng)緩慢,幼仔死亡率高。
并且如果這還不夠令人震驚,第三代中的一些小鼠毛發(fā)甚至生長(zhǎng)在嘴里——一種罕見(jiàn)的現(xiàn)象,但顯然在食用轉(zhuǎn)基因大豆倉(cāng)鼠中,這種現(xiàn)象更普遍。
這項(xiàng)研究由Surov供職的俄羅斯科學(xué)院生態(tài)和進(jìn)化研究所和基因安全國(guó)家協(xié)會(huì)聯(lián)合執(zhí)行,預(yù)計(jì)3個(gè)月后(2010年7月)發(fā)表結(jié)果——因此該技術(shù)細(xì)節(jié)拭目以待。但Surov在發(fā)給我的電子郵件中勾勒出基本的內(nèi)容。
他把具有快速繁殖率的坎貝爾倉(cāng)鼠分為4組。所有的按標(biāo)準(zhǔn)飲食喂養(yǎng),但一組的飲食中沒(méi)有任何大豆,另一組食用非轉(zhuǎn)基因大豆,第三組食用轉(zhuǎn)基因大豆,第四組食物中所含的轉(zhuǎn)基因大豆數(shù)量最大。每個(gè)實(shí)驗(yàn)組有5對(duì)倉(cāng)鼠,每對(duì)生產(chǎn)7-8胎,共140只。
Surov 告訴俄羅斯之聲,
“最初,一切順利。然而,當(dāng)我們從它們的幼仔中重新選擇配對(duì)并按照之前的方案喂養(yǎng)時(shí),我們注意到一個(gè)相當(dāng)嚴(yán)重的影響。這些成對(duì)的幼仔生長(zhǎng)速度較慢,達(dá)到他們的性成熟期緩慢。”
他從每組選擇新的配對(duì),會(huì)產(chǎn)生的另39只幼仔。對(duì)照組產(chǎn)仔52只,非轉(zhuǎn)基因大豆組產(chǎn)仔78只。食用轉(zhuǎn)基因大豆組,只有40個(gè)幼仔出生。而其中,25%死亡。與對(duì)照組相比,死亡率是對(duì)照組5%死亡率的5倍。食用轉(zhuǎn)基因大豆含量最高的那組倉(cāng)鼠,只有一只雌鼠生產(chǎn)。它她生產(chǎn)了16個(gè)幼崽,約20%死亡。
Surov說(shuō):“F2 [第三代]代的低的數(shù)字顯示,許多動(dòng)物不育?!?/p>
發(fā)表的論文還將包括第三代動(dòng)物器官的大小尺寸,包括睪丸,脾,子宮等。如果該團(tuán)隊(duì)能籌集足夠的資金,他們也將分析收集的血液樣本中的激素水平。
毛發(fā)生長(zhǎng)在口中
今年早些時(shí)候,Surov以共同作者身份在《生物科學(xué)報(bào)告》發(fā)表了一篇論文,展示了罕見(jiàn)的實(shí)例,毛發(fā)生長(zhǎng)在倉(cāng)鼠的口中。
有些袋包含單一的毛;有些,厚束的無(wú)色或色素毛發(fā)達(dá)到牙齒的咀嚼表面。有時(shí)候,牙齒被整齊的發(fā)束在兩側(cè)包圍。毛發(fā)垂直生長(zhǎng),末端銳利,往往覆蓋著一團(tuán)粘液“
(這些毛束的照片真正惡心。相信我,或你自己尋找。)
在研究結(jié)論中,作者推測(cè),這種驚人的缺陷可能是由于實(shí)驗(yàn)室倉(cāng)鼠的飲食造成的。他們寫(xiě)道,“該病變會(huì)因天然食品中的元素缺乏而惡化,如轉(zhuǎn)基因(GM)的成分(轉(zhuǎn)基因大豆或玉米粉)或污染物(殺蟲(chóng)劑,毒枝菌素,重金屬等)。 “事實(shí)上,口中長(zhǎng)毛的倉(cāng)鼠數(shù)量在食用轉(zhuǎn)基因大豆的倉(cāng)鼠的第三代中比例較高,遠(yuǎn)遠(yuǎn)高于Surov以前在任何地方見(jiàn)過(guò)的動(dòng)物。
初步的,但是不吉利的
Surov警告不要過(guò)早下結(jié)論。他說(shuō),“很可能,轉(zhuǎn)基因食品本身并不導(dǎo)致這些影響。” Surov希望優(yōu)先進(jìn)行飼料成分分析,發(fā)現(xiàn)是什么原因造成這些影響并且如何影響。
除了轉(zhuǎn)基因生物,可能是污染物,他說(shuō),或高濃度除草劑殘留,如農(nóng)達(dá)(Roundup)。事實(shí)上,這些大豆含有高濃度的農(nóng)達(dá)(Roundup),他們是所謂的“抗農(nóng)達(dá)”。細(xì)菌的基因被整合到它們的DNA所以植株可以容忍孟山都的農(nóng)達(dá)除草劑。因此,轉(zhuǎn)基因大豆總是攜帶者高濃度的除草劑的雙重威脅,伴隨著基因工程帶來(lái)的任何副作用的。
轉(zhuǎn)基因生物飼料造成多年的生殖障礙
Surov的倉(cāng)鼠只是最近的動(dòng)物在消費(fèi)轉(zhuǎn)基因食品之后患有生殖紊亂。2005年,Irina Ermakova,也與俄羅斯國(guó)家科學(xué)院一起報(bào)告,喂養(yǎng)轉(zhuǎn)基因大豆的母鼠后代有超過(guò)一半的幼仔在三周內(nèi)死亡。這一死亡率也是5倍于非轉(zhuǎn)基因大豆組的死亡率10%。轉(zhuǎn)基因組的幼仔也更?。ㄒ?jiàn)照片),無(wú)法生育。
講述一件巧合的事,在Ermakova的飼養(yǎng)試驗(yàn)之后,她的實(shí)驗(yàn)室開(kāi)始喂食飼養(yǎng)設(shè)施中的所有大鼠轉(zhuǎn)基因大豆。兩個(gè)月內(nèi),幼仔死亡率達(dá)到55%。
當(dāng)Ermakova喂食雄性大鼠轉(zhuǎn)基因大豆,雄性大鼠睪丸從正常的粉紅色轉(zhuǎn)變?yōu)樯钏{(lán)色!意大利科學(xué)家在試驗(yàn)小鼠身上發(fā)現(xiàn)同樣的變化,包括受損的初級(jí)精子細(xì)胞。此外,喂食轉(zhuǎn)基因大豆親本小鼠的胚胎DNA功能不全。
2008年11月奧地利政府發(fā)表的研究表明,轉(zhuǎn)基因玉米喂養(yǎng)的小鼠,吃的轉(zhuǎn)基因玉米越多,后代的數(shù)量及個(gè)體就越小。
愛(ài)荷華州中部農(nóng)民Jerry Rosman飼養(yǎng)的豬和牛出現(xiàn)麻煩,變成不育。他飼養(yǎng)的一些豬甚至假懷孕或生下水袋。經(jīng)過(guò)幾個(gè)月的調(diào)查和試驗(yàn),他終于追蹤到問(wèn)題源于轉(zhuǎn)基因玉米飼料。每次報(bào)紙,雜志,或電視節(jié)目報(bào)道Jerry的問(wèn)題,他將接到更多的農(nóng)民的電話(huà)抱怨他們的農(nóng)場(chǎng)的牲畜不育,與轉(zhuǎn)基因玉米有關(guān)。
貝勒醫(yī)學(xué)院的研究人員偶然發(fā)現(xiàn),飼養(yǎng)在玉米棒子作為草墊的大鼠“既不繁殖也不展示生殖行為?!庇衩撞牧显囼?yàn)揭示兩種化合物”在濃度大約比傳統(tǒng)植物雌激素低兩百倍時(shí)“終止了雌鼠的性周期。一種化合物也縮減了雄鼠的性行為,這兩種物質(zhì)促進(jìn)乳腺癌和前列腺癌細(xì)胞的增長(zhǎng)。研究人員發(fā)現(xiàn),這些物質(zhì)的數(shù)量隨轉(zhuǎn)基因玉米品種不同而變化。在貝勒醫(yī)學(xué)院用的壓碎的玉米芯很可能來(lái)自愛(ài)荷華州中部,靠近Jerry Rosman和其他的農(nóng)場(chǎng),這些農(nóng)場(chǎng)抱怨牲畜不育。
在印度的哈里亞納邦,獸醫(yī)的調(diào)查報(bào)告說(shuō),食用轉(zhuǎn)基因棉籽的水牛遭受不育,以及頻繁的流產(chǎn),早產(chǎn)和子宮脫垂的痛苦。許多成年和幼年的牛也離奇死亡。
否定,攻擊,并取消后續(xù)
發(fā)現(xiàn)轉(zhuǎn)基因生物不利結(jié)果的科學(xué)家均定期遭受攻擊,嘲笑,拒絕提供資金,甚至被解雇。當(dāng)Ermakova報(bào)告食用轉(zhuǎn)基因大豆動(dòng)物的后代嬰兒死亡率高,例如,她呼吁科學(xué)界重復(fù)并驗(yàn)證她的初步結(jié)果。她還要求更多的資金來(lái)分析保留的器官。相反,她受到攻擊和詆毀。樣品從她的實(shí)驗(yàn)室被盜,論文在她的辦公桌上被燒毀,她說(shuō),她的老板,從他的老板那里受到壓力,告訴她不要再做任何更多的轉(zhuǎn)基因生物研究。還沒(méi)有人一再重復(fù)Ermakova的簡(jiǎn)單,廉價(jià)的研究。
在試圖向她表示同情,她的一位同事建議,或許對(duì)轉(zhuǎn)基因大豆將解決超越人口的問(wèn)題!
Surov報(bào)道,到目前為止,他還沒(méi)有受到任何壓力。
選擇退出大規(guī)模轉(zhuǎn)基因生物飼養(yǎng)試驗(yàn)
如果沒(méi)有詳細(xì)的測(cè)試,沒(méi)有人能夠查出究竟是什么原因造成俄羅斯倉(cāng)鼠和大鼠,意大利和奧地利小鼠,印度和美國(guó)的牲畜的生殖悲劇。我們只能推測(cè)轉(zhuǎn)基因食品在1996年被引進(jìn),與相應(yīng)的低出生體重嬰兒的比例高漲,不育不孕癥,其他美國(guó)人口問(wèn)題之間的聯(lián)系。但許多科學(xué)家,醫(yī)師和有關(guān)人士并不認(rèn)為公眾應(yīng)繼續(xù)為生物技術(shù)產(chǎn)業(yè)的大規(guī)模無(wú)節(jié)制的試驗(yàn)而保留實(shí)驗(yàn)室動(dòng)物。
Alexey Surov表示,“我們沒(méi)有權(quán)利使用轉(zhuǎn)基因生物,直到我們了解可能產(chǎn)生的不利影響,不僅對(duì)自己,而且對(duì)后代。我們一定要全面詳細(xì)地研究以澄清這一點(diǎn)。任何類(lèi)型的污染必須在消費(fèi)之前進(jìn)行測(cè)試,轉(zhuǎn)基因食品(生物)只是其中之一。”
GM soy linked to sterility, infant mortality
Wednesday, 21 April 2010 20:09
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Genetically Modified Soy Linked to Sterility, Infant Mortality
Jeffrey Smith
Huffington Post, April 20 2010
http://www.huffingtonpost.com/jeffrey-smith/genetically-modified-soy_b_544575.html
"This study was just routine," said Russian biologist Alexey V. Surov, in what could end up as the understatement of this century. Surov and his colleagues set out to discover if Monsanto"s genetically modified (GM) soy, grown on 91% of US soybean fields, leads to problems in growth or reproduction. What he discovered may uproot a multi-billion dollar industry.
After feeding hamsters for two years over three generations, those on the GM diet, and especially the group on the maximum GM soy diet, showed devastating results. By the third generation, most GM soy-fed hamsters lost the ability to have babies. They also suffered slower growth, and a high mortality rate among the pups.
And if this isn"t shocking enough, some in the third generation even had hair growing inside their mouths—a phenomenon rarely seen, but apparently more prevalent among hamsters eating GM soy.
The study, jointly conducted by Surov"s Institute of Ecology and Evolution of the Russian Academy of Sciences and the National Association for Gene Security, is expected to be published in three months (July 2010)—so the technical details will have to wait. But Surov sketched out the basic set up for me in an email.
He used Campbell hamsters, with a fast reproduction rate, divided into 4 groups. All were fed a normal diet, but one was without any soy, another had non-GM soy, a third used GM soy, and a fourth contained higher amounts of GM soy. They used 5 pairs of hamsters per group, each of which produced 7-8 litters, totally 140 animals.
Surov told The Voice of Russia,
"Originally, everything went smoothly. However, we noticed quite a serious effect when we selected new pairs from their cubs and continued to feed them as before. These pairs" growth rate was slower and reached their sexual maturity slowly."
He selected new pairs from each group, which generated another 39 litters. There were 52 pups born to the control group and 78 to the non-GM soy group. In the GM soy group, however, only 40 pups were born. And of these, 25% died. This was a fivefold higher death rate than the 5% seen among the controls. Of the hamsters that ate high GM soy content, only a single female hamster gave birth. She had 16 pups; about 20% died.
Surov said "The low numbers in F2 [third generation] showed that many animals were sterile."
The published paper will also include measurements of organ size for the third generation animals, including testes, spleen, uterus, etc. And if the team can raise sufficient funds, they will also analyze hormone levels in collected blood samples.
Hair Growing in the Mouth
Earlier this year, Surov co-authored a paper in Doklady Biological Sciences showing that in rare instances, hair grows inside recessed pouches in the mouths of hamsters.
"Some of these pouches contained single hairs; others, thick bundles of colorless or pigmented hairs reaching as high as the chewing surface of the teeth. Sometimes, the tooth row was surrounded with a regular brush of hair bundles on both sides. The hairs grew vertically and had sharp ends, often covered with lumps of a mucous."
(The photos of these hair bundles are truly disgusting. Trust me, or look for yourself.)
At the conclusion of the study, the authors surmise that such an astounding defect may be due to the diet of hamsters raised in the laboratory. They write, "This pathology may be exacerbated by elements of the food that are absent in natural food, such as genetically modified (GM) ingredients (GM soybean or maize meal) or contaminants (pesticides, mycotoxins, heavy metals, etc.)." Indeed, the number of hairy mouthed hamsters was much higher among the third generation of GM soy fed animals than anywhere Surov had seen before.
Preliminary, but Ominous
Surov warns against jumping to early conclusions. He said, "It is quite possible that the GMO does not cause these effects by itself." Surov wants to make the analysis of the feed components a priority, to discover just what is causing the effect and how.
In addition to the GMOs, it could be contaminants, he said, or higher herbicide residues, such as Roundup. There is in fact much higher levels of Roundup on these beans; they"re called "Roundup Ready." Bacterial genes are forced into their DNA so that the plants can tolerate Monsanto"s Roundup herbicide. Therefore, GM soy always carries the double threat of higher herbicide content, couple with any side effects of genetic engineering.
Years of Reproductive Disorders from GMO-Feed
Surov"s hamsters are just the latest animals to suffer from reproductive disorders after consuming GMOs. In 2005, Irina Ermakova, also with the Russian National Academy of Sciences, reported that more than half the babies from mother rats fed GM soy died within three weeks. This was also five times higher than the 10% death rate of the non-GMO soy group. The babies in the GM group were also smaller (see photo) and could not reproduce.
In a telling coincidence, after Ermakova"s feeding trials, her laboratory started feeding all the rats in the facility a commercial rat chow using GM soy. Within two months, the infant mortality facility-wide reached 55%.
When Ermakova fed male rats GM soy, their testicles changed from the normal pink to dark blue! Italian scientists similarly found changes in mice testes (PDF), including damaged young sperm cells. Furthermore, the DNA of embryos from parent mice fed GM soy functioned differently.
An Austrian government study published in November 2008 showed that the more GM corn was fed to mice, the fewer the babies they had (PDF), and the smaller the babies were.
Central Iowa Farmer Jerry Rosman also had trouble with pigs and cows becoming sterile. Some of his pigs even had false pregnancies or gave birth to bags of water. After months of investigations and testing, he finally traced the problem to GM corn feed. Every time a newspaper, magazine, or TV show reported Jerry"s problems, he would receive calls from more farmers complaining of livestock sterility on their farm, linked to GM corn.
Researchers at Baylor College of Medicine accidentally discovered that rats raised on corncob bedding "neither breed nor exhibit reproductive behavior." Tests on the corn material revealed two compounds that stopped the sexual cycle in females "at concentrations approximately two-hundredfold lower than classical phytoestrogens." One compound also curtailed male sexual behavior and both substances contributed to the growth of breast and prostate cancer cell cultures. Researchers found that the amount of the substances varied with GM corn varieties. The crushed corncob used at Baylor was likely shipped from central Iowa, near the farm of Jerry Rosman and others complaining of sterile livestock.
In Haryana, India, a team of investigating veterinarians report that buffalo consuming GM cottonseed suffer from infertility, as well as frequent abortions, premature deliveries, and prolapsed uteruses. Many adult and young buffalo have also died mysteriously.
Denial, Attack and Canceled Follow-up
Scientists who discover adverse findings from GMOs are regularly attacked, ridiculed, denied funding, and even fired. When Ermakova reported the high infant mortality among GM soy fed offspring, for example, she appealed to the scientific community to repeat and verify her preliminary results. She also sought additional funds to analyze preserved organs. Instead, she was attacked and vilified. Samples were stolen from her lab, papers were burnt on her desk, and she said that her boss, under pressure from his boss, told her to stop doing any more GMO research. No one has yet repeated Ermakova"s simple, inexpensive studies.
In an attempt to offer her sympathy, one of her colleagues suggested that maybe the GM soy will solve the over population problem!
Surov reports that so far, he has not been under any pressure.
Opting Out of the Massive GMO Feeding Experiment
Without detailed tests, no one can pinpoint exactly what is causing the reproductive travesties in Russian hamsters and rats, Italian and Austrian mice, and livestock in India and America. And we can only speculate about the relationship between the introduction of genetically modified foods in 1996, and the corresponding upsurge in low birth weight babies, infertility, and other problems among the US population. But many scientists, physicians, and concerned citizens don"t think that the public should remain the lab animals for the biotech industry"s massive uncontrolled experiment.
Alexey Surov says, "We have no right to use GMOs until we understand the possible adverse effects, not only to ourselves but to future generations as well. We definitely need fully detailed studies to clarify this. Any type of contamination has to be tested before we consume it, and GMO is just one of them."

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